This is a framework molecular model kit of the Amino Acid Isoleucine. This is part of our new line of MicroMolecules that are one half the scale of our regular framework molecular models at 0.5 inch per 1 Angstrom. The finished molecule literally fits in the palm of your hand. No assembly required. Stay tuned for the release of all of the amino acids and other series soon to come
It is essential in humans, meaning the body cannot synthesize it, and must be ingested in our diet. Isoleucine is synthesized from pyruvate employing leucine biosynthesis enzymes in other organisms such as bacteria.
Isoleucine, like other branched-chain amino acids, is associated with insulin resistance: higher levels of isoleucine are observed in the blood of diabetic mice, rats, and humans. Mice fed an isoleucine deprivation diet for one day have improved insulin sensitivity, and feeding of an isoleucine deprivation diet for one week significantly decreases blood glucose levels. In diet-induced obese and insulin resistant mice, a diet with decreased levels of isoleucine (with or without the other branched-chain amino acids) results in reduced adiposity and improved insulin sensitivity. Reduced dietary levels of isoleucine are required for the beneficial metabolic effects of a low protein diet. In humans, a protein restricted diet lowers blood levels of isoleucine and decreases fasting blood glucose levels. In humans, higher dietary levels of isoleucine are associated with greater body mass index.
CAUTION: THESE MOLECULES CONTAIN MANY SMALL PARTS NOT SUITABLE FOR CHILDREN UNDER 5 YEARS OF AGE.
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